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Found 1 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2/G1/S-specific cyclin-E1' and Ligand = 'BDBM7257'
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Sugen

LigandPNGBDBM7257((3Z)-5-fluoro-3-({4-oxo-2H,4H,5H,6H,7H-pyrrolo[3,4...)
Affinity DataIC50:  300nMpH: 7.4 T: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed