Found 7 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 6/G1/S-specific cyclin-D1' and Ligand = 'BDBM6309' TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 0.980nMAssay Description:The standard Lance Ultra method was performed by a 10 μL enzyme reaction system containing 0.3 nM CDK4/cyclin D1 protein, 50 nM ULight-4E-BP1 po...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK6/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 3.80nMAssay Description:Inhibition of CDK6/cyclinD1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK6/cyclin-D1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK6/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK6/cyclin D1 (unknown origin) using RBER-CHKtide as substrate measured after 1 hr by ADP-glo luminescence assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) using ULight-MBP peptide substrate in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
