Found 2 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 8' and Ligand = 'BDBM50248614' 
Affinity DataEC50: 1.30nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
Affinity DataKd: 46nMAssay Description:Binding affinity to partial length wild-type human CDK8 (M1 to T360residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
