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Found 4 Enz. Inhib. hit(s) with Target = 'Cysteine protease ATG4B' and Ligand = 'BDBM50536838'
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536838(CHEMBL4520267)
Affinity DataIC50:  73nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536838(CHEMBL4520267)
Affinity DataIC50:  80nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536838(CHEMBL4520267)
Affinity DataIC50:  163nMAssay Description:Inhibition of N-terminal His6/SUMO-tagged full length human ATG4B expressed in Escherichia coli BL21 (DE3) cells using His-LC3B-GST as substrate prei...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536838(CHEMBL4520267)
Affinity DataIC50:  360nMAssay Description:Inhibition of ATG4B (unknown origin) using FRETGATE-16 as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed