Found 4 Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM100205'
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 870nMAssay Description:Activity of human CFTR F508 deletion mutant expressed in FRT cells assessed as potentiation of genistein-induced iodine ion influx after 24 hrs by YF...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataKd: 700nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Binding affinity to human CFTR F508 deletion mutant expressed in FRT cells assessed as increase in iodine influx after 16 to 20 hrs by fluorescence a...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 708nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair