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Found 6 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4/3A5' and Ligand = 'BDBM50538344'
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate measured for 10 to 30 mins in presence of NADPH regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed