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Found
1
Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM184155'
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Actelion Pharmaceuticals
US Patent
Ligand
BDBM184155
(US9150566, 193)
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Affinity Data
IC50: 600nM
pH: 7.4 T: 2°C
Assay Description:
The CYP3A4 inhibition assay was performed using human liver microsomes and testosterone 6'-hydroxylation as a P450 isoform-specific marker. In a tota...
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Ligand Info
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