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Found 1 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM21160'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21160(N-[(5-methylpyrimidin-2-yl)methyl]-6-phenyl-2-(pyr...)
Affinity DataIC50:  71nMpH: 7.4 T: 2°CAssay Description:The inhibition of recombinant human CYP3A4 was measured as the ability to perform a debenzylation of 7-benzyloxy-4-trifluoromethylcoumarin (BFC). Bef...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed