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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM50008760'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50008760(CHEMBL3236364)
Affinity DataIC50:  1.83nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50008760(CHEMBL3236364)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed