Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50527972'
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human D2R expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after 120 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataIC50: >5.00E+4nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter® βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 R...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataEC50: >1.00E+4nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter® βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 R...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human D2R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed