Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50085331'
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  5.20nMAssay Description:Binding Affinity was tested on the high affinity site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  23nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  350nMAssay Description:Dissociation constant of compound on one-site model Human Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  590nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  720nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataEC50:  4.40nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataEC50:  7.70nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed