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Found 7 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM50211362'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM50211362(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)
Affinity DataIC50:  473nMAssay Description:Inhibition of human recombinant DAAO expressed in Escherichia coli assessed as H2O2 production from D-serine degradation after 30 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM50211362(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human DAAOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM50211362(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human D-amino acid oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Sus scrofa (pig))
North-West University

Curated by ChEMBL
LigandPNGBDBM50211362(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)
Affinity DataIC50:  933nMAssay Description:Inhibition of porcine kidney DAAO using D-serine as substrate assessed as H2O2 formation by amplex red and peroxidase-coupled continuous fluorescence...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD-amino-acid oxidase(Sus scrofa (pig))
North-West University

Curated by ChEMBL
LigandPNGBDBM50211362(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)
Affinity DataIC50:  933nMAssay Description:Inhibition of porcine kidney DAAO using D-serine as substrate by Amplex red and horseradish peroxidase fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM50211362(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)
Affinity DataKd:  900nMAssay Description:Binding affinity to human recombinant DAAO by kinetic study scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM50211362(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)
Affinity DataKd:  617nMAssay Description:Binding affinity to human recombinant DAAO by isothermal titration calorimeter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed