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Found 6 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM50433371'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433371(CHEMBL2375519)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433371(CHEMBL2375519)
Affinity DataIC50:  219nMAssay Description:Competitive inhibition of human recombinant DAAO after 1 hr by coupled enzyme assay in presence of D-serineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433371(CHEMBL2375519)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to human recombinant DAAO at 600 nm spectral modification by spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433371(CHEMBL2375519)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to human recombinant DAAO at 492 nm spectral modification by spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433371(CHEMBL2375519)
Affinity DataKd:  4.80E+3nMAssay Description:Binding affinity to human recombinant DAAO at 440 nm spectral modification by spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433371(CHEMBL2375519)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to human recombinant DAAO by stopped flow spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed