Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 1' and Ligand = 'BDBM50357280'
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50357280(CHEMBL1916517)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human recombinant DNMT1 expressed in Sf9 cells assessed as incorporation of [3H]S-adenosyl methionine into hemimethylated oligonucleoti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50357280(CHEMBL1916517)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed