Found 3 Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 1' and Ligand = 'BDBM50389497' TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of DNMT (unknown origin) by densitometric analysisMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
