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Found 4 Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 3B' and Ligand = 'BDBM50075103'
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  500nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  500nMAssay Description:Inhibition of human DNMT3B using [3H]-SAMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  730nMAssay Description:Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells by DRONE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells using CpG site containing internally quenched hairpin oligonucl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed