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Found 1 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-alpha' and Ligand = 'BDBM246603'
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Medical University

LigandPNGBDBM246603(DNA topoisomerase inhibitor, 5)
Affinity DataIC50:  2.50E+5nMpH: 7.8 T: 2°CAssay Description:Supercoiled pHOT1 DNA (0.5 μg) was incubated with four units of human topoisomerase I in relaxation buffer (10mM Tris-HCl (pH 7.8), 1mM EDTA, 0.15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed