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Found 1 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-alpha' and Ligand = 'BDBM50123623'
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123623((R)-13-(3-aminopyrrolidin-1-yl)-12-fluoro-10-oxo-1...)
Affinity DataIC50:  60nMAssay Description:Induction of poison effect at DNA topoisomerase 2 by G-quadruplex interaction polymerase stop assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed