Found 3 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 4 subunit A/B' and Ligand = 'BDBM50393503' TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus RN4220 DNA topoisomerase 4 expressed in Escherichia coli BL21(DE3) cells using supercoiled pBR322 DNA as substrat...More data for this Ligand-Target Pair
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based microtiter plate ...More data for this Ligand-Target Pair
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
