Found 2 Enz. Inhib. hit(s) with Target = 'DNA-(apurinic or apyrimidinic site) endonuclease' and Ligand = 'BDBM203861'
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy Of Sciences
Curated by ChEMBL
Russian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human APE1 using double-stranded DNA as substrate preincubated for 15 mins followed by substrate addition measured at 1 min...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy Of Sciences
Curated by ChEMBL
Russian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 250nMpH: 7.5Assay Description:In this assay, the complementary single-stranded oligonucleotides at 100
μm were mixed at a 1:1 ratio and annealed in assay buffer (50 mm Tris
pH ...More data for this Ligand-Target Pair