Found 3 Enz. Inhib. hit(s) with Target = 'DNA-(apurinic or apyrimidinic site) endonuclease' and Ligand = 'BDBM318445' TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataKi: 190nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant His-6 tagged human APE1 expressed in Escherichia coli C41(DE3) using 5'-(F)-CGACTXTTGAATTGACACGCCATGTCGATCAATTCAATAGTCG-(D)...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 2.90E+3nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
