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Found 3 Enz. Inhib. hit(s) with Target = 'DNA-(apurinic or apyrimidinic site) endonuclease' and Ligand = 'BDBM50030282'
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50030282(CHEBI:51052 | Lucanthone)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human APE1 after 25 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50030282(CHEBI:51052 | Lucanthone)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of full length human APE1 expressed in Escherichia coli BL21/DE3 assessed as inhibition of incision of depurinated supercoiled pUC18 plasm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50030282(CHEBI:51052 | Lucanthone)
Affinity DataKd:  89nMAssay Description:Binding affinity to full length human APE1 expressed in Escherichia coli BL21/DE3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank