Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Diacylglycerol kinase alpha' and Ligand = 'BDBM43868'
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...)
Affinity DataIC50:  300nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...)
Affinity DataIC50:  300nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Sus scrofa)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Sus scrofa)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed