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Found 3 Enz. Inhib. hit(s) with Target = 'Diacylglycerol kinase zeta' and Ligand = 'BDBM50541811'
TargetDiacylglycerol kinase zeta(Homo sapiens)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541811(CHEMBL4637336)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase zeta(Homo sapiens)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541811(CHEMBL4637336)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase zeta(Homo sapiens)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541811(CHEMBL4637336)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed