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Found
1
Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM476663'
Target
Dihydrofolate reductase
(Homo sapiens (Human))
University of Connecticut
US Patent
Ligand
BDBM476663
(US10870625, Compound 29)
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Affinity Data
IC50: 1.96E+3nM
Assay Description:
Enzyme activity and inhibition assays were performed by monitoring the NADPH-dependent reduction of dihydrofolate catalyzed by the DHFR enzyme. The r...
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