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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM497336'
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM497336(US11001595, Compound 9 | US11111252, Compound 9)
Affinity DataIC50:  234nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM497336(US11001595, Compound 9 | US11111252, Compound 9)
Affinity DataIC50:  234nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM497336(US11001595, Compound 9 | US11111252, Compound 9)
Affinity DataIC50:  1.10E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM497336(US11001595, Compound 9 | US11111252, Compound 9)
Affinity DataIC50:  1.10E+3nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent