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Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50014707'
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataKi:  0.00520nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibitory activity of the compound towards Dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed