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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50461742'
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50461742(CHEMBL4226465)
Affinity DataIC50:  219nMAssay Description:Inhibition of Pneumocystis jirovecii recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50461742(CHEMBL4226465)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of human recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB