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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM477573'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics

US Patent
LigandPNGBDBM477573((S)—N-(1-(2-Fluorophenyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  6.36E+3nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics

US Patent
LigandPNGBDBM477573((S)—N-(1-(2-Fluorophenyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate measured for 68 mins by DCIP based colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed