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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM477607'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM477607(4-bromo-N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahy...)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate measured for 68 mins by DCIP based colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM477607(4-bromo-N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahy...)
Affinity DataIC50:  39nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent