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Found 1 Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [489-587,M535I,L552P,A560V,V571F,I573V]' and Ligand = 'BDBM4690'
TargetDimer of Gag-Pol polyprotein [489-587,M535I,L552P,A560V,V571F,I573V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4690((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.000420nM ΔG°:  -71.8kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed