Found 7 Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50177232'
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Pharmacopeia
Curated by ChEMBL
Pharmacopeia
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against Farnesyltransferase quantified by modified SPA assay with improved sensitivityMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Pharmacopeia
Curated by ChEMBL
Pharmacopeia
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against Ha-Ras processing in COS7 cellsMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Pharmacopeia
Curated by ChEMBL
Pharmacopeia
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against farnesyltransferase quantified by SPA assayMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Pharmacopeia
Curated by ChEMBL
Pharmacopeia
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against Ha-Ras processing in COS7 cellsMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Pharmacopeia
Curated by ChEMBL
Pharmacopeia
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against Ha-Ras processing in COS7 cellsMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Pharmacopeia
Curated by ChEMBL
Pharmacopeia
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibitory activity against farnesyltransferase quantified by SPA assayMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Pharmacopeia
Curated by ChEMBL
Pharmacopeia
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibitory activity against farnesyltransferase quantified by SPA assayMore data for this Ligand-Target Pair