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Found 7 Enz. Inhib. hit(s) with Target = 'Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C' and Ligand = 'BDBM14362'
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition cGMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cAMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  3.40E+6nMAssay Description:Inhibition of fraction I of guinea pig phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed