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Found 10 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK1' and Ligand = 'BDBM50347750'
TargetDual specificity protein kinase CLK1(Mus musculus)
Universite£? De Rennes 1

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  15nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universite£? De Rennes 1

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  23nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universite£? De Rennes 1

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  35nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant human CLK1 expressed in Sf9 insect cells using myelin basic protein as substrate incubated for 110 mins in presence of ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universite£? De Rennes 1

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  71nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  71nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  71nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  77nMAssay Description:Inhibition of recombinant human CLK1 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataKd:  75nMAssay Description:Binding affinity to CLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataKd:  8.5nMAssay Description:Binding affinity to human CLK1 assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed