Found 1 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP' and Ligand = 'BDBM50401474'
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 26.7nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair