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Found 1 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP [124-240]' and Ligand = 'BDBM240883'
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240883(US9409888, 23)
Affinity DataIC50:  0.429nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent