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Found 4 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50579861'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50579861(CHEMBL5085118)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) preincubated for 60 mins followed by substrate addition and further incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50579861(CHEMBL5085118)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of wild type EGFR (unknown origin) preincubated for 60 mins followed by substrate addition and further incubated for 60 mins in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50579861(CHEMBL5085118)
Affinity DataEC50:  12nMAssay Description:Inhibition of EGF-induced phosphorylation of EGFR T790M/L858R double mutant in human NCI-H1975 cells preincubated for 120 mins followed by EGF stimul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50579861(CHEMBL5085118)
Affinity DataEC50:  165nMAssay Description:Inhibition of EGF-induced phosphorylation of wild type EGFR in human NCI-H1975 cells preincubated for 120 mins followed by EGF stimulation and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed