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Found 4 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50119582'
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50119582(CHEMBL3617743 | US10413545, Compound 40 | US971881...)
Affinity DataIC50:  178nMAssay Description:Inhibition of fatty acid synthase (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50119582(CHEMBL3617743 | US10413545, Compound 40 | US971881...)
Affinity DataIC50:  178nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50119582(CHEMBL3617743 | US10413545, Compound 40 | US971881...)
Affinity DataIC50:  178nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50119582(CHEMBL3617743 | US10413545, Compound 40 | US971881...)
Affinity DataIC50:  347nMAssay Description:Inhibition of fatty acid synthase keto-reductase domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed