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Found 2 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM373525'
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM373525(US10421747, Compound 7 | US9902714, Compound 7)
Affinity DataKd:  340nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan® technologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM373525(US10421747, Compound 7 | US9902714, Compound 7)
Affinity DataKd:  340nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent