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Found 4 Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM155544'
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155544(US9012461, 20)
Affinity DataIC50:  0.810nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155544(US9012461, 20)
Affinity DataIC50:  5nMpH: 7.0Assay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155544(US9012461, 20)
Affinity DataIC50:  30nMT: 2°CAssay Description:Adult human dermal lymphatic microvascular endothelial cells (HMVEC-dLyAD) (Cat# CC-2810, Lonza) were seeded into clear-bottom, TC treated 12 well pl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155544(US9012461, 20)
Affinity DataKd:  0.630nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In DepthDetails US Patent