Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Folate receptor beta' and Ligand = 'BDBM50354833'
TargetFolate receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to human FRbeta expressed in Chinese hamster D4 cells assessed as antiproliferative activity measured as reduction in cell growth af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 0.170nMAssay Description:Binding affinity to human FRbeta expressed in Chinese hamster D4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetFolate receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of FRbeta (unknown origin) expressed in Chinese hamster D4 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-bl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetFolate receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 30nMAssay Description:Binding affinity to human FR2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 126nMAssay Description:Binding affinity to human FRbeta expressed in Chinese hamster D4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetFolate receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FRbeta (unknown origin) expressed in Chinese hamster D4 cells assessed as cell growth inhibition incubated up to 96 hrs in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed