Found 6 Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 35' and Ligand = 'BDBM50357187'
Affinity DataKi: 655nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution as...More data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+4nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at GPR35 in human HT-29 cells assessed as induction of cell desensitization to 1 uM zaprinast preincubated for 1 hr followed by zapr...More data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+4nMAssay Description:Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcrip...More data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assayMore data for this Ligand-Target Pair