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Found 7 Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 35' and Ligand = 'BDBM61632'
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  160nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human Gal4-VP16 fused GPR35 expressed in human U2OS cells assessed as beta arrestin translocation by reporter gene assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  500nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  574nMAssay Description:Antagonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells after 90 mins by beta-arrestin recruitment...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  1.39E+3nMAssay Description:Data Source: Dr. Mary Abood Source Affiliation: Temple University Network: NIH Molecular Libraries Probe Production Centers Network (MLPCN) Grant Pro...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  1.04E+4nMAssay Description:Antagonist activity at human GPR35 expressed in human HT29 cells after 1 hr by DMR assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed