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Found
1
Enz. Inhib. hit(s) with Target = 'GTP-binding protein Rheb' and Ligand = 'BDBM554622'
Target
GTP-binding protein Rheb
(Homo sapiens (Human))
Navitor Pharmaceuticals
US Patent
Ligand
BDBM554622
(US11339144, Compound I-75)
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Affinity Data
IC50: <1.00E+4nM
Assay Description:
For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...
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Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Ligand Info
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Details
US Patent
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