Found 12 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50242325' 
Affinity DataIC50: 42nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Inhibition of phosphorylated ERK2 (unknown origin) using myelin basic protein as substrate after 2 hrs in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Affinity DataKd: 250nMAssay Description:Binding affinity to human wild type N-terminal His/AVi-tagged biotinylated KRas expressed in Escherichia coli BL21 (DE3) in presence of GDP by SPR as...More data for this Ligand-Target Pair
Affinity DataKd: 42nMAssay Description:Displacement of BODIPY-FL-GD from human wild type KRAS (Met1 to Lys169 residues) incubated for over 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 58nMAssay Description:Binding affinity to human wild type N-terminal His/AVi-tagged biotinylated KRas expressed in Escherichia coli BL21 (DE3) in presence of GDP by SPR as...More data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) using FAM-labelled peptide as substrate in presence of Tween20 by fluorescence polarization ass...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Displacement of BODIPY-FL-GD from human KRAS G12D (Met1 to Lys169 residues) incubated for over 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Displacement of BODIPY-FL-GD from human KRAS G12C (Met1 to Lys169 residues) incubated for over 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human wild type N-terminal His/AVi-tagged biotinylated KRas expressed in Escherichia coli BL21 (DE3) in presence of GTP by SPR as...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human wild type N-terminal His/AVi-tagged biotinylated KRas expressed in Escherichia coli BL21 (DE3) in presence of GTP by SPR as...More data for this Ligand-Target Pair
