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Found 2 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50496837'
TargetGTPase KRas(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50496837(CHEMBL3218641)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant HA-tagged K-Ras G12V mutant (unknown origin) assessed as disruption of interaction with GST-tagged Raf-RBD after overnight ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50496837(CHEMBL3218641)
Affinity DataKd:  830nMAssay Description:Binding affinity to K-Ras G12V mutant (unknown origin) after 2 hrs by fluorescence polarization-based spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed