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Found 2 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50579094'
TargetGTPase KRas(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579094(CHEMBL4867496)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579094(CHEMBL4867496)
Affinity DataKd:  140nMAssay Description:Binding affinity to GppNHp bound His6-tagged KRas G12V mutant (1 to 186 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed