Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'GTPase NRas [G12C]' and Ligand = 'BDBM591397'
TargetGTPase NRas [G12C](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591397(Synthesis of two atropisomers of (2S)-N-[(8S,14S,2...)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase NRas [G12C](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591397(Synthesis of two atropisomers of (2S)-N-[(8S,14S,2...)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent