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Found
1
Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]' and Ligand = 'BDBM27578'
Target
Gag-Pol polyprotein [588-1027]
(Human immunodeficiency virus type 1 group M subtyp...)
Pfizer
Ligand
BDBM27578
(5-{[7-(hydroxymethyl)-3-methyl-1H-indazol-4-yl]oxy...)
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Affinity Data
IC50: 71nM
pH: 7.8 T: 2°C
Assay Description:
The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...
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Target Info
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Ligand Info
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Article
PubMed
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