Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-1' and Ligand = 'BDBM50000766'
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
In Depth
Date in BDB:
12/27/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha1 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  16nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  16.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  16.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  30.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKd:  36nMAssay Description:Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  38nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  53nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000766BDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  193nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)